Fig. 10. Cd increases PGE₂ levels in a ROS, p38 and COX-2 dependent pathway. HT-29 cells were pre-treated with NAC, SB202190 or CLX for 30 minutes followed by Cd (100 nM) for 6 hours. PGE₂ levels were measured using ELISA kit. Values are represented as the mean of fold change ± SEM of n=3. * denotes p<0.05.